I have two concerns:

My boyfriend claims psychedelics open your mind to new ideas/perspectives and help you experience the "spiritual world." I maintain that anything you see or think is just a result from a brain overloaded on chemicals. However, I am beginning to feel closed-minded, and I would like to have your opinion on psychedelics — are they beneficial if used for a one-time experience, and will they immediately/permanently alter the way I view the world and myself? Given that I have doubts, should I even try anything this mind-altering? I have read your answers pertaining to short-/long-term effects, but I wanted to know if there was any actual evidence of the beneficial effects.

Many of my friends take Adderall while they drink. What are the possible health risks of doing this? I know Adderall is a stimulant, so can you drink much more alcohol while on it without feeling the effects as much?

I want to know what it is when you spontaneously trip without dropping tabs or anything. I've never had any drugs except marijuana. It is weird. I know that tripping is an induced psychosis, so am I psychotic or what? I was seeing a shrink and will be going back into treatment next semester. I think substance use is boring and a complete copout on life. I've made a lot of discoveries without needing to trip. Why does this happen? Tell me what you know.

Does acid (LSD) have a detrimental affect on women who use the birth control pill? Is it possible for a woman to be impregnated by pre-ejaculatory fluids four days after the menstrual cycle after unprotected sex?

A friend of mine has an essential tremor disorder. She smokes weed almost everyday because she said it helps her to stop shaking. She tried all kind of medicines doctors have prescribed her, and botox and acupuncture. None of them helped her. Any advice?

I've heard that drinking coffee and grapefruit juice at around the same time can extend the effects of caffeine. Is this true? I know that grapefruits can increase the bioavailability of some drugs... what about caffeine? Is this at all dangerous?

Are the health risks of drinking Red Bull and vodka in moderation (two to three) drinks an evening any greater than drinking two or three rum and Cokes, or two or three anything and Mountain Dew?

My girlfriend tells me she uses marijuana to calm herself if she is having a stressful day. She has been doing this for many years. She says smoking pot is like self-medicating — it is better than using anti-depressants. She also claims smoking pot helps with depression because of how it helps produce serotonin in the body. What is serotonin and how does it help depression? Does smoking pot really help with managing your anxiety, depression, etc.?